Human SLC4A4 activation kit by CRISPRa

CAT#: GA105750

SLC4A4 CRISPRa kit - CRISPR gene activation of human solute carrier family 4 member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC4A4
• Locus ID: 8671
• Kit Components:

  GA105750G1, SLC4A4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105750G2, SLC4A4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105750G3, SLC4A4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001098484, NM_001134742, NM_003759
• Synonyms: hhNMC; HNBC1; KNBC; NBC1; NBC2; NBCe1-A; pNBC; SLC4A5
• Summary: This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]