Human SERPINB7 activation kit by CRISPRa

CAT#: GA105779

SERPINB7 CRISPRa kit - CRISPR gene activation of human serpin family B member 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SERPINB7
• Locus ID: 8710
• Kit Components:

  GA105779G1, SERPINB7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105779G2, SERPINB7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105779G3, SERPINB7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040147, NM_001261830, NM_001261831, NM_003784
• Synonyms: MEGSIN; PPKN; TP55
• Summary: This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]