Human EDF1 activation kit by CRISPRa

CAT#: GA105787

EDF1 CRISPRa kit - CRISPR gene activation of human endothelial differentiation related factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EDF1
• Locus ID: 8721
• Kit Components:

  GA105787G1, EDF1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105787G2, EDF1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105787G3, EDF1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001281297, NM_001281298, NM_001281299, NM_003792, NM_153200
• Synonyms: CFAP280; EDF-1; MBF1
• Summary: This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]