Human C19orf2 (URI1) activation kit by CRISPRa

CAT#: GA105791

URI1 CRISPRa kit - CRISPR gene activation of human URI1 prefoldin like chaperone

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: URI1
• Locus ID: 8725
• Kit Components:

  GA105791G1, URI1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105791G2, URI1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105791G3, URI1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252641, NM_003796, NM_134447, NR_045557
• Synonyms: C19orf2; NNX3; PPP1R19; RMP; URI
• Summary: This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011]