Human RIP (RIPK1) activation kit by CRISPRa

CAT#: GA105801

RIPK1 CRISPRa kit - CRISPR gene activation of human receptor interacting serine/threonine kinase 1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol RIPK1
Locus ID 8737
Kit Components

GA105801G1, RIPK1 gRNA vector 1 in pCas-Guide-CRISPRa

GA105801G2, RIPK1 gRNA vector 2 in pCas-Guide-CRISPRa

GA105801G3, RIPK1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001317061, NM_003804, NM_001354930, NM_001354931, NM_001354932, NM_001354933, NM_001354934
Synonyms RIP; RIP-1; RIP1
Summary This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.