Human ADAM9 activation kit by CRISPRa

CAT#: GA105814

ADAM9 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 9

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADAM9
• Locus ID: 8754
• Kit Components:

  GA105814G1, ADAM9 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105814G2, ADAM9 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105814G3, ADAM9 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001005845, NM_003816, NR_027638, NR_027639, NR_027878
• Synonyms: KIAA0021; MCMP; MDC9; Mltng
• Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]