Human Alpha SNAP (NAPA) activation kit by CRISPRa

CAT#: GA105826

NAPA CRISPRa kit - CRISPR gene activation of human NSF attachment protein alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NAPA
• Locus ID: 8775
• Kit Components:

  GA105826G1, NAPA gRNA vector 1 in pCas-Guide-CRISPRa

  GA105826G2, NAPA gRNA vector 2 in pCas-Guide-CRISPRa

  GA105826G3, NAPA gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003827, NR_038456, NR_038457
• Synonyms: SNAPA
• Summary: This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]