Human CREG1 activation kit by CRISPRa

CAT#: GA105850

CREG1 CRISPRa kit - CRISPR gene activation of human cellular repressor of E1A stimulated genes 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CREG1
• Locus ID: 8804
• Kit Components:

  GA105850G1, CREG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105850G2, CREG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105850G3, CREG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003851
• Synonyms: CREG
• Summary: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008]