Human IL1RL2 activation kit by CRISPRa

CAT#: GA105853

IL1RL2 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL1RL2
• Locus ID: 8808
• Kit Components:

  GA105853G1, IL1RL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105853G2, IL1RL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105853G3, IL1RL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003854, NM_001351446, NM_001351447, NM_001351448, NM_001351449, NM_001351450
• Synonyms: IL-1Rrp2; IL-36R; IL1R-rp2; IL1RRP2
• Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]