Human ST3GAL5 activation kit by CRISPRa

CAT#: GA105903

ST3GAL5 CRISPRa kit - CRISPR gene activation of human ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ST3GAL5
• Locus ID: 8869
• Kit Components:

  GA105903G1, ST3GAL5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105903G2, ST3GAL5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105903G3, ST3GAL5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042437, NM_003896, NM_001354223, NM_001354224, NM_001354226, NM_001354227, NM_001354229, NM_001354233, NM_001354234, NM_001354238, NM_001354247, NM_001354248, NM_001363847
• Synonyms: SATI; SIAT9; SIATGM3S; SPDRS; ST3GalV
• Summary: Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]