Human ARHGEF7 activation kit by CRISPRa

CAT#: GA105907

ARHGEF7 CRISPRa kit - CRISPR gene activation of human Rho guanine nucleotide exchange factor 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARHGEF7
• Locus ID: 8874
• Kit Components:

  GA105907G1, ARHGEF7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105907G2, ARHGEF7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105907G3, ARHGEF7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001113511, NM_001113512, NM_001113513, NM_001320851, NM_001320852, NM_001320853, NM_001320854, NM_001330597, NM_001330598, NM_003899, NM_145735, NM_001354046, NM_001354047, NM_001354048, NM_001354049, NM_001354050, NM_001354051, NM_001354052, NM_001354053, NM_001354054, NM_001354055, NM_001354056, NM_001354057, NM_001354058, NM_001354059, NM_001354060, NM_001354061
• Synonyms: BETA-PIX; COOL-1; COOL1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PIXB
• Summary: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016]