Human EIF2B4 activation kit by CRISPRa

CAT#: GA105921

EIF2B4 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2B subunit delta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF2B4
• Locus ID: 8890
• Kit Components:

  GA105921G1, EIF2B4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105921G2, EIF2B4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105921G3, EIF2B4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001034116, NM_001318965, NM_001318966, NM_001318967, NM_001318968, NM_001318969, NM_015636, NM_172195
• Synonyms: EIF-2B; EIF2B; EIF2Bdelta
• Summary: Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]