Human eIF2B epsilon (EIF2B5) activation kit by CRISPRa

CAT#: GA105924

EIF2B5 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 2B subunit epsilon

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF2B5
• Locus ID: 8893
• Kit Components:

  GA105924G1, EIF2B5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105924G2, EIF2B5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105924G3, EIF2B5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003907
• Synonyms: CACH; CLE; EIF-2B; EIF2Bepsilon; LVWM
• Summary: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]