Human AP1M1 activation kit by CRISPRa

CAT#: GA105935

AP1M1 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 1 subunit mu 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AP1M1
• Locus ID: 8907
• Kit Components:

  GA105935G1, AP1M1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105935G2, AP1M1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105935G3, AP1M1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130524, NM_032493
• Synonyms: AP47; CLAPM2; CLTNM; MU-1A
• Summary: The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]