Human N WASP (WASL) activation kit by CRISPRa

CAT#: GA105972

WASL CRISPRa kit - CRISPR gene activation of human WASP like actin nucleation promoting factor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WASL
• Locus ID: 8976
• Kit Components:

  GA105972G1, WASL gRNA vector 1 in pCas-Guide-CRISPRa

  GA105972G2, WASL gRNA vector 2 in pCas-Guide-CRISPRa

  GA105972G3, WASL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003941
• Synonyms: N-WASP; NWASP; WASPB
• Summary: This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]