Human KALRN activation kit by CRISPRa

CAT#: GA105984

KALRN CRISPRa kit - CRISPR gene activation of human kalirin RhoGEF kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KALRN
• Locus ID: 8997
• Kit Components:

  GA105984G1, KALRN gRNA vector 1 in pCas-Guide-CRISPRa

  GA105984G2, KALRN gRNA vector 2 in pCas-Guide-CRISPRa

  GA105984G3, KALRN gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001024660, NM_003947, NM_007064, NR_028136, NM_001322988, NM_001322989, NM_001322990, NM_001322991, NM_001322992, NM_001322993, NM_001322994, NM_001322995, NM_001322996, NM_001322997, NM_001322998, NM_001322999, NM_001323000, NM_001323001
• Synonyms: ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD
• Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]