Human SLC25A14 activation kit by CRISPRa

CAT#: GA105991

SLC25A14 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC25A14
• Locus ID: 9016
• Kit Components:

  GA105991G1, SLC25A14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105991G2, SLC25A14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105991G3, SLC25A14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282195, NM_001282196, NM_001282197, NM_001282198, NM_003951, NM_022810, NR_104107
• Synonyms: BMCP1; UCP5
• Summary: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013]