Human CLIC3 activation kit by CRISPRa

CAT#: GA105995

CLIC3 CRISPRa kit - CRISPR gene activation of human chloride intracellular channel 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLIC3
• Locus ID: 9022
• Kit Components:

  GA105995G1, CLIC3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105995G2, CLIC3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105995G3, CLIC3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004669
• Synonyms: chloride intracellular channel 3; OTTHUMP00000022630
• Summary: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008]