Human Claudin 2 (CLDN2) activation kit by CRISPRa

CAT#: GA106037

CLDN2 CRISPRa kit - CRISPR gene activation of human claudin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLDN2
• Locus ID: 9075
• Kit Components:

  GA106037G1, CLDN2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106037G2, CLDN2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106037G3, CLDN2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171092, NM_001171095, NM_020384
• Synonyms: SP82
• Summary: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]