Human ARHI (DIRAS3) activation kit by CRISPRa

CAT#: GA106039

DIRAS3 CRISPRa kit - CRISPR gene activation of human DIRAS family GTPase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DIRAS3
• Locus ID: 9077
• Kit Components:

  GA106039G1, DIRAS3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106039G2, DIRAS3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106039G3, DIRAS3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004675
• Synonyms: ARHI; NOEY2
• Summary: This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015]