Human PKMYT1 activation kit by CRISPRa

CAT#: GA106049

PKMYT1 CRISPRa kit - CRISPR gene activation of human protein kinase, membrane associated tyrosine/threonine 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PKMYT1
• Locus ID: 9088
• Kit Components:

  GA106049G1, PKMYT1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106049G2, PKMYT1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106049G3, PKMYT1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258450, NM_001258451, NM_004203, NM_182687
• Synonyms: MYT1; PPP1R126
• Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]