Human FCP1 (CTDP1) activation kit by CRISPRa

CAT#: GA106101

CTDP1 CRISPRa kit - CRISPR gene activation of human CTD phosphatase subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTDP1
• Locus ID: 9150
• Kit Components:

  GA106101G1, CTDP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106101G2, CTDP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106101G3, CTDP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001202504, NM_001318511, NM_004715, NM_048368
• Synonyms: CCFDN; FCP1
• Summary: This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]