Human SLC28A1 activation kit by CRISPRa

CAT#: GA106104

SLC28A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 28 member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC28A1
• Locus ID: 9154
• Kit Components:

  GA106104G1, SLC28A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106104G2, SLC28A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106104G3, SLC28A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001287761, NM_001287762, NM_001321721, NM_001321722, NM_004213, NM_201651
• Synonyms: CNT1; HCNT1
• Summary: Sodium-dependent and pyrimidine-selective. Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). It also transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine. [UniProtKB/Swiss-Prot Function]