Human Exonuclease 1 (EXO1) activation kit by CRISPRa

CAT#: GA106105

EXO1 CRISPRa kit - CRISPR gene activation of human exonuclease 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EXO1
• Locus ID: 9156
• Kit Components:

  GA106105G1, EXO1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106105G2, EXO1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106105G3, EXO1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001319224, NM_003686, NM_006027, NM_130398
• Synonyms: HEX1; hExoI
• Summary: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]