Human EDG4 (LPAR2) activation kit by CRISPRa

CAT#: GA106113

LPAR2 CRISPRa kit - CRISPR gene activation of human lysophosphatidic acid receptor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LPAR2
• Locus ID: 9170
• Kit Components:

  GA106113G1, LPAR2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106113G2, LPAR2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106113G3, LPAR2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004720
• Synonyms: EDG-4; EDG4; LPA-2; LPA2
• Summary: This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]