Human ST2 (IL1RL1) activation kit by CRISPRa

CAT#: GA106115

IL1RL1 CRISPRa kit - CRISPR gene activation of human interleukin 1 receptor like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IL1RL1
• Locus ID: 9173
• Kit Components:

  GA106115G1, IL1RL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106115G2, IL1RL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106115G3, IL1RL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282408, NM_003856, NM_016232, NM_173459, NR_104167
• Synonyms: DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1
• Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]