Human BUB3 activation kit by CRISPRa

CAT#: GA106123

BUB3 CRISPRa kit - CRISPR gene activation of human BUB3 mitotic checkpoint protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BUB3
• Locus ID: 9184
• Kit Components:

  GA106123G1, BUB3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106123G2, BUB3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106123G3, BUB3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001007793, NM_004725
• Synonyms: BUB3L; hBUB3
• Summary: This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]