Human Aurora B (AURKB) activation kit by CRISPRa

CAT#: GA106142

AURKB CRISPRa kit - CRISPR gene activation of human aurora kinase B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AURKB
• Locus ID: 9212
• Kit Components:

  GA106142G1, AURKB gRNA vector 1 in pCas-Guide-CRISPRa

  GA106142G2, AURKB gRNA vector 2 in pCas-Guide-CRISPRa

  GA106142G3, AURKB gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256834, NM_001284526, NM_001313950, NM_001313951, NM_001313952, NM_001313953, NM_001313954, NM_001313955, NM_004217, NR_132730, NR_132731
• Synonyms: AIK2; AIM-1; AIM1; ARK2; AurB; aurkb-sv1; aurkb-sv2; IPL1; PPP1R48; STK5; STK12
• Summary: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]