Human FAIM3 (FCMR) activation kit by CRISPRa

CAT#: GA106144

FCMR CRISPRa kit - CRISPR gene activation of human Fc fragment of IgM receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCMR
• Locus ID: 9214
• Kit Components:

  GA106144G1, FCMR gRNA vector 1 in pCas-Guide-CRISPRa

  GA106144G2, FCMR gRNA vector 2 in pCas-Guide-CRISPRa

  GA106144G3, FCMR gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142472, NM_001142473, NM_001193338, NM_005449
• Synonyms: Fas apoptotic inhibitory molecule 3; OTTHUMP00000034619; regulator of Fas-induced apoptosis; TOSO
• Summary: Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]). [supplied by OMIM, Jul 2010]