Human PIWIL1 activation kit by CRISPRa

CAT#: GA106184

PIWIL1 CRISPRa kit - CRISPR gene activation of human piwi like RNA-mediated gene silencing 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIWIL1
• Locus ID: 9271
• Kit Components:

  GA106184G1, PIWIL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106184G2, PIWIL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106184G3, PIWIL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190971, NM_004764
• Synonyms: CT80.1; HIWI; MIWI; PIWI
• Summary: This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]