Human BCL7B activation kit by CRISPRa

CAT#: GA106186

BCL7B CRISPRa kit - CRISPR gene activation of human BAF chromatin remodeling complex subunit BCL7B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BCL7B
• Locus ID: 9275
• Kit Components:

  GA106186G1, BCL7B gRNA vector 1 in pCas-Guide-CRISPRa

  GA106186G2, BCL7B gRNA vector 2 in pCas-Guide-CRISPRa

  GA106186G3, BCL7B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001197244, NM_001301061, NM_001707, NM_138707, NR_036682
• Summary: This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010]