Human SNAP29 activation kit by CRISPRa

CAT#: GA106228

SNAP29 CRISPRa kit - CRISPR gene activation of human synaptosome associated protein 29

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNAP29
• Locus ID: 9342
• Kit Components:

  GA106228G1, SNAP29 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106228G2, SNAP29 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106228G3, SNAP29 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004782
• Synonyms: CEDNIK; SNAP-29
• Summary: This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]