Human SLC9A3R2 activation kit by CRISPRa

CAT#: GA106234

SLC9A3R2 CRISPRa kit - CRISPR gene activation of human SLC9A3 regulator 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC9A3R2
• Locus ID: 9351
• Kit Components:

  GA106234G1, SLC9A3R2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106234G2, SLC9A3R2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106234G3, SLC9A3R2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130012, NM_001252073, NM_001252075, NM_001252076, NM_004785
• Synonyms: E3KARP; NHE3RF2; NHERF-2; NHERF2; OCTS2; SIP-1; SIP1; TKA-1
• Summary: This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]