Human Adiponectin (ADIPOQ) activation kit by CRISPRa

CAT#: GA106250

ADIPOQ CRISPRa kit - CRISPR gene activation of human adiponectin, C1Q and collagen domain containing

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADIPOQ
• Locus ID: 9370
• Kit Components:

  GA106250G1, ADIPOQ gRNA vector 1 in pCas-Guide-CRISPRa

  GA106250G2, ADIPOQ gRNA vector 2 in pCas-Guide-CRISPRa

  GA106250G3, ADIPOQ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177800, NM_004797
• Synonyms: ACDC; ACRP30; ADIPQTL1; ADPN; APM-1; APM1; GBP28
• Summary: This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]