Human PEX16 activation kit by CRISPRa

CAT#: GA106279

PEX16 CRISPRa kit - CRISPR gene activation of human peroxisomal biogenesis factor 16

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PEX16
• Locus ID: 9409
• Kit Components:

  GA106279G1, PEX16 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106279G2, PEX16 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106279G3, PEX16 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004813, NM_057174
• Synonyms: PBD8A; PBD8B
• Summary: The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described. [provided by RefSeq, Jul 2008]