Human CDYL activation kit by CRISPRa

CAT#: GA106293

CDYL CRISPRa kit - CRISPR gene activation of human chromodomain Y like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDYL
• Locus ID: 9425
• Kit Components:

  GA106293G1, CDYL gRNA vector 1 in pCas-Guide-CRISPRa

  GA106293G2, CDYL gRNA vector 2 in pCas-Guide-CRISPRa

  GA106293G3, CDYL gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143970, NM_001143971, NM_004824, NM_170751, NM_170752, NR_026590, NM_001368126, NM_001368125, NM_001368127
• Synonyms: CDYL1
• Summary: Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]