Human GGPS1 activation kit by CRISPRa

CAT#: GA106313

GGPS1 CRISPRa kit - CRISPR gene activation of human geranylgeranyl diphosphate synthase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GGPS1
• Locus ID: 9453
• Kit Components:

  GA106313G1, GGPS1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106313G2, GGPS1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106313G3, GGPS1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001037277, NM_001037278, NM_004837, NR_036605
• Synonyms: GGPPS; GGPPS1
• Summary: This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]