Human EIF4EL3 (EIF4E2) activation kit by CRISPRa

CAT#: GA106327

EIF4E2 CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 4E family member 2

SDS

  See Other Versions

Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

Other products for "EIF4E2"

Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol EIF4E2
Locus ID 9470
Kit Components

GA106327G1, EIF4E2 gRNA vector 1 in pCas-Guide-CRISPRa

GA106327G2, EIF4E2 gRNA vector 2 in pCas-Guide-CRISPRa

GA106327G3, EIF4E2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001276336, NM_001276337, NM_001282958, NM_001330201, NM_001330202, NM_001330203, NM_004846
Synonyms 4E-LP; 4EHP; EIF4EL3; IF4e
Summary Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
KN401391 EIF4E2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.