Human ROCK2 activation kit by CRISPRa

CAT#: GA106331

ROCK2 CRISPRa kit - CRISPR gene activation of human Rho associated coiled-coil containing protein kinase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ROCK2
• Locus ID: 9475
• Kit Components:

  GA106331G1, ROCK2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106331G2, ROCK2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106331G3, ROCK2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001321643, NM_004850
• Synonyms: ROCK-II
• Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]