Human SLC4A7 activation kit by CRISPRa

CAT#: GA106347

SLC4A7 CRISPRa kit - CRISPR gene activation of human solute carrier family 4 member 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC4A7
• Locus ID: 9497
• Kit Components:

  GA106347G1, SLC4A7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106347G2, SLC4A7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106347G3, SLC4A7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258379, NM_001258380, NM_003615, NM_001321103, NM_001321104, NM_001321105, NM_001321106, NM_001321107, NM_001321108, NR_135541, NR_135542, NR_135543, NR_135544
• Synonyms: NBC2; NBC3; NBCN1; SBC2; SLC4A6
• Summary: This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]