Human MAGED1 activation kit by CRISPRa

CAT#: GA106350

MAGED1 CRISPRa kit - CRISPR gene activation of human MAGE family member D1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAGED1
• Locus ID: 9500
• Kit Components:

  GA106350G1, MAGED1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106350G2, MAGED1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106350G3, MAGED1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001005332, NM_001005333, NM_006986
• Synonyms: DLXIN-1; NRAGE
• Summary: This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]