Human TBPL1 activation kit by CRISPRa

CAT#: GA106365

TBPL1 CRISPRa kit - CRISPR gene activation of human TATA-box binding protein like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TBPL1
• Locus ID: 9519
• Kit Components:

  GA106365G1, TBPL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106365G2, TBPL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106365G3, TBPL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253676, NM_004865
• Synonyms: MGC:8389; MGC:9620; STUD; TLF; TLP; TRF2
• Summary: This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Nov 2011]