Human NPEPPS activation kit by CRISPRa

CAT#: GA106366

NPEPPS CRISPRa kit - CRISPR gene activation of human aminopeptidase puromycin sensitive

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NPEPPS
• Locus ID: 9520
• Kit Components:

  GA106366G1, NPEPPS gRNA vector 1 in pCas-Guide-CRISPRa

  GA106366G2, NPEPPS gRNA vector 2 in pCas-Guide-CRISPRa

  GA106366G3, NPEPPS gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006310, NM_001330257
• Synonyms: AAP-S; MP100; PSA
• Summary: This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle. [provided by RefSeq, Jul 2008]