Human MPDU1 activation kit by CRISPRa

CAT#: GA106371

MPDU1 CRISPRa kit - CRISPR gene activation of human mannose-P-dolichol utilization defect 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MPDU1
• Locus ID: 9526
• Kit Components:

  GA106371G1, MPDU1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106371G2, MPDU1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106371G3, MPDU1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004870, NR_024603, NM_001330073
• Synonyms: CDGIF; HBEBP2BPA; Lec35; My008; PP3958; PQLC5; SL15
• Summary: This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]