Human CDC42 Binding Protein Kinase Beta (CDC42BPB) activation kit by CRISPRa

CAT#: GA106413

CDC42BPB CRISPRa kit - CRISPR gene activation of human CDC42 binding protein kinase beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CDC42BPB
• Locus ID: 9578
• Kit Components:

  GA106413G1, CDC42BPB gRNA vector 1 in pCas-Guide-CRISPRa

  GA106413G2, CDC42BPB gRNA vector 2 in pCas-Guide-CRISPRa

  GA106413G3, CDC42BPB gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006035
• Synonyms: MRCKB
• Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]