Human MAD2L1 binding protein (MAD2L1BP) activation kit by CRISPRa

CAT#: GA106421

MAD2L1BP CRISPRa kit - CRISPR gene activation of human MAD2L1 binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: MAD2L1BP
• Locus ID: 9587
• Kit Components:

  GA106421G1, MAD2L1BP gRNA vector 1 in pCas-Guide-CRISPRa

  GA106421G2, MAD2L1BP gRNA vector 2 in pCas-Guide-CRISPRa

  GA106421G3, MAD2L1BP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001003690, NM_014628
• Synonyms: CMT2
• Summary: The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]