Human CART (CARTPT) activation kit by CRISPRa

CAT#: GA106432

CARTPT CRISPRa kit - CRISPR gene activation of human CART prepropeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CARTPT
• Locus ID: 9607
• Kit Components:

  GA106432G1, CARTPT gRNA vector 1 in pCas-Guide-CRISPRa

  GA106432G2, CARTPT gRNA vector 2 in pCas-Guide-CRISPRa

  GA106432G3, CARTPT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004291
• Synonyms: CART
• Summary: This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans. [provided by RefSeq, Feb 2016]