Human ABCG1 activation kit by CRISPRa

CAT#: GA106441

ABCG1 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily G member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCG1
• Locus ID: 9619
• Kit Components:

  GA106441G1, ABCG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106441G2, ABCG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106441G3, ABCG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004915, NM_016818, NM_207174, NM_207627, NM_207628, NM_207629, NM_207630
• Synonyms: ABC8; WHITE1
• Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008]