Human NUP155 activation kit by CRISPRa

CAT#: GA106450

NUP155 CRISPRa kit - CRISPR gene activation of human nucleoporin 155

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUP155
• Locus ID: 9631
• Kit Components:

  GA106450G1, NUP155 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106450G2, NUP155 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106450G3, NUP155 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278312, NM_004298, NM_153485
• Synonyms: ATFB15; N155
• Summary: Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]