Human SOCS5 activation kit by CRISPRa

CAT#: GA106472

SOCS5 CRISPRa kit - CRISPR gene activation of human suppressor of cytokine signaling 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOCS5
• Locus ID: 9655
• Kit Components:

  GA106472G1, SOCS5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106472G2, SOCS5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106472G3, SOCS5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_014011, NM_144949
• Synonyms: CIS6; Cish5; CISH6; SOCS-5
• Summary: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]